Hey read this do not know if they can do cats although I found a article about cats but they would not let me paste it, interesting really check it out before doing and I would contact another vet just to check......
FDA Approves Use of Neutersol for Male Puppies
June 6, 2003
By Brian Sodergren
Giving a new meaning to the term "shrinkage," the Food and Drug Administration (FDA) took the first step toward the chemical sterilization of pets—i.e. non-surgical spaying or neutering—by recently approving the use of Neutersol for male puppies. The testicle and prostate-shrinking drug is already available at some veterinary clinics for about the same price as a surgical sterilization.
Neutersol approval has been a long time in coming. The HSUS has been actively involved in pursuing alternatives to surgical spaying and neutering for decades, and worked with the late Dr. Mostafa S. Fahim, the developer of Neutersol, in early field trials of the product.
In contrast to the standard surgical castration, which removes the testicles, Neutersol is a zinc and l-arginine-based compound injected into each testicle, causing them and the prostate to shrivel. With just one quick shot, the solution causes permanent sterility. While anesthesia may be needed for the procedure—which, at this point, is approved only for male dogs age three to ten months—the time your pooch spends at the veterinarian will probably be somewhat shorter.
"Some people are uncomfortable with surgery and anesthesia," said Dr. Bruce Addison, the founder of Addison Biological Laboratory, which markets the drug. Addison hopes that the ease of Neutersol will entice more people to sterilize their pets and help solve the pet overpopulation problem.
The use of Neutersol, however, will not completely stop testosterone production in dogs, leaving open the possibility that the drug will not eliminate hormone-related disease such as testicular cancer or prostate disease. Both possibilities are eliminated when a dog is surgically neutered.
Addison said that they are addressing these things with the FDA, and that while he didn't want to get ahead of the agency's review of its research, he feels that testicular cancer is not an issue because Neutersol atrophies the testicles by 77 percent, eliminating most of the cells that could potentially cause cancer.
Another concern is that the continued production of testosterone may not decrease unwanted secondary behavioral characteristics, such as roaming, marking or aggression, which surgical castration is thought to tackle. While Neutersol's 41% to 52% decrease in testosterone levels could also have some of the same positive behavioral effects as surgical castration, no tests have been done comparing dog behavior and the use of the drug. In fact, the drug, on its packaging, claims that as with surgical neutering, Neutersol may not alter unwanted male behaviors.
Side effects to the drug include testicle swelling within 24 hours of injection, which is a normal reaction to the compound; other potential side effects include vomiting, loss of appetite, lethargy, and diarrhea.
"Although this product is limited in scope, we're excited about the FDA approving this first step in chemical sterilization," says Stephanie Shain, Director of Companion Animal Outreach at The HSUS. "For people who may be unnecessarily squeamish about having their dog surgically neutered, Neutersol may be a suitable alternative for them to explore."
Given Neutersol's limited usage for puppies, Addison said that they are moving forward with testing on older dogs and cats. Scientists have tried chemical sterilization on these populations in the past, but the results thus far have been mixed. If you have an older dog who is not neutered, your best bet is not to wait until chemical sterilization is available, Shain says, but instead to talk with your veterinarian to have dog altered the "old fashioned" way.
With the number of dogs and cats entering animal shelters reaching eight million annually, and almost half of them being euthanized, unplanned and irresponsible breeding make the pet overpopulation problem one that also costs taxpayers millions, Shain notes. By taking the time to neuter or spay your pets, she adds, you are doing your part to end the tragedy of unwanted pets.
Because Neutersol is such a new product, many veterinarians may not yet have it in stock. Based on those who do, however, it is expected to cost about the same as surgical neutering. Your veterinarian can fully explain the benefits of neutering to you, along with the best age at which to sterilize your pet, and whether you should go the chemical or surgical route.